Vitamin B3 or Niacin acts as a powerful agent to improve the condition of erectile dysfunction and a research study conducted in a medical center of Hong Kong confirmed that Niacin supplementation has resulted in the increase of blood flow across the pelvic region in men. A slight niacin flush should end in about ten minutes or so. While low pH environments may cause niacinamide to turn into niacin, this shouldn’t impact the efficacy of niacinamide. Yes, niacin is good for erectile dysfunction. Foods highest in niacin include: organ meat (liver, heart, kidneys), chicken, beef, fish, venison, and whole grains. I will start by saying the first time I took niacin I took around 500mg which is high dose and for my weight (+-65kg, female) it was way too powerful, within 10 minutes I felt a whole body flush, i was hot and red and tingly all over! The Surprising Nootropic Benefits of Niacin and Niacinamide Niacinamide has been generating headlines in the nootropic community over the past few months. OK, I know what you’re thinking, “Isn’t Niacin just another vitamin?”And the answer is yes but it’s not to be taken lightly. Niacinamide is an awesome jack-of-all-trades ingredient. It's usually taken with (twice as … Plant topics can vary from aromatic plants to psychoactive plants, herbalism and medicine making, as well as your experiences on Plant Medicines (including plant extracts) Post some images of the medicines your growing or making, ask away on any plant related query you may have and welcome to r/plantmedicines :), Press J to jump to the feed. Learn about side effects, warnings, dosage, and more. Those who have intimacy problems may also benefit from niacin. I'm the dumbass who took 500mg the first time and I thought I was having some kind of allergic reaction/heart attack. The human body can also make niacin from the amino acid tryptophan, according to the National Institutes of Health (NIH). When added to skin care products, niacinamide treats rosacea and reduces red blotchiness. Lightens dark spots (hyperpigmentation) and evens skin tone 4, 5, 6, Improves overall skin health (barrier function) 7, 8, 9, which may help in the treatment of general redness, May reduce sebum - which means it can be good for oily skin 10. (2013). Doing so is using niacin as a drug, not a … Ross described it as a feeling of warmth, itching, redness or a tingly feeling under the skin. What is Niacin? Niacin can also lower triglycerides by 20–50% (9). Cookies help us deliver our Services. One of the biggest benefits of niacin is its ability to balance blood sugar levels and help control diabetes symptoms. Like other B vitamins, niacin helps the body break down carbohydrates, fats and proteins into energy, according to the University of Maryland Medical Center. Dermatology Research And Practice, 2011, 1-5. doi:10.1155/2011/379173, 7 - Draelos, Z.D., Ertel, K.D., & Berge, C.A. (Angiogenic means the formation and development of blood vessels.). Everyday: Daily Help Thread stickied to the top of the sub! PMCID: PMC3724370, 4 - Chiu, P., Chan, C., Lin, H., & Chiu, H. (2007). and u/ginsengbear’s list of 2-5% niacinamide products! When rats with ischemic stroke were given niacin, their brains grew new blood vessels, according to researchers at Henry Ford Hospital in Detroit, Michigan. Niacin did not result in the hypothesised reduced heart attacks and strokes. ". The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. In this episode, I describe why I don’t recommend using niacin in this way. It doesn’t require a special routine order and it has low irritation potential, so it’s typically an easy and safe ingredient to introduce. International Journal Of Dermatology, 52(8), 999-1004. doi:10.1111/ijd.12002, 2 - Shalita, A., Smith, J., Parish, L., Sofman, M., & Chalker, D. (1995). British Journal Of Dermatology, 147(1), 20-31. doi:10.1046/j.1365-2133.2002.04834.x, 6 - Navarrete-Solís, J., Castanedo-Cázares, J., Torres-Álvarez, B., Oros-Ovalle, C., Fuentes-Ahumada, C., & González, F. et al. Niacin has many health benefits, so before we leap into why exactly it is so good for bodybuilding let’s look at why niacin is essential for a healthy body. Vitamin B3 may also be helpful to cancer patients. The authors of the article state that more research is needed before niacin ends its term as a cholesterol therapy mainstay. In addition, it plays a role in gland and liver function. Abram Hoffer, one of the pioneers of the use of diet and nutritional supplements to treat schizophrenia, worked with more than 5,000 schizophrenic patients over a 50-year period. Niacin also has beneficial effects for rosacea, which is a skin condition that … More severe niacin deficiency can cause a condition called pellagra. Most Olay moisturizers (1-5% according to the safety data sheets), Superdrug Calm Skin De-Stress Refreshing Facial Spritz (>5%), Skinlex 10% Niacinamide Serum (Minimalistic & Extended versions) (10%), Paula’s Choice 10% Niacinamide Booster (10%). Research on the use of oral niacin to treat specific conditions shows: 1. More importantly, however, Niacin can RUIN your liver, if you go above the recommended dosage. And it is well established that niacin helps reduce harmful cholesterol levels in the bloodstream. Your friend is misinformed. Niacinamide is an awesome jack-of-all-trades ingredient. Many people use niacin supplements to reduce their methylation rate. Make sure to have reasonable expectations for your skin before changing your routine! Myth 1: Niacin is able to detoxify the liver. https://www.isom.ca/wp-content/uploads/2013/01/Niacin-for-Detoxification-A-Little-known-Therapeutic-Use-26.2.pdf check out this link for the detoxification benefits!! A recent animal study suggested that niacin may be helpful in preventing inflammatory bowel disease and colitis. People have been using niacin (vitamin B3) to cure depression and anxiety for years now. Try one of these 12 best niacinamide serums from brands like The Ordinary, Paula's Choice, and more. According to the University of Maryland Medical Center, symptoms of mild niacin deficiency include fatigue, canker sores, vomiting, depression, poor circulation and indigestion. Other side effects can include stomach upset, intestinal gas, dizziness and pain in the mouth, the NIH reported. Some studies have found the taking niacin may help stroke patients. It may be good for other skin conditions, too. Niacin and niacinamide – better known as Vitamin B3 – have shown some surprising cognitive benefits during … Also known as: Slo-Niacin, Niaspan, B-3-50, B3-500-Gr, Niacin SR Endur-acin HDL Benefit Niacor Niacin has an average rating of 8.7 out of 10 from a total of 38 ratings for the treatment of Depression. As a treatment, higher amounts of niacin can improve cholesterol levels and lower cardiovascular risks. I now take 150-200mg for a flush, upping the dose only if I don't get results, it is a powerful detoxifier and is even used to flush the system of heavy metals and nasty chemical contamination. In some cases, niacin is prescribed along with certain cholesterol medications to control high cholesterol. Like other B vitamins, niacin helps the body break down carbohydrates, fats and proteins into energy, according to the University of Maryland Medical Center. Niacin takes longer to act, than to be able to provide immediate effects, to eliminate THC from the body. Niacinamide can be found in all product types - moisturizers, serums, toners, etc. International journal of pharmaceutics, 441 1-2, 192-201. doi:10.1016/j.ijpharm.2012.11.043, 10 - Zoe Diana Draelos, Akira Matsubara, & Kenneth Smiles. Check out the skin concerns section of the wiki index for more ingredient recommendations for common skin concerns. Niacin is known to boost the water content in the skin – and this can be achieved by topically applying nicotinamide cream. I 2nd the benefits of using Niacin for recovery too. Well that depends on the product! Niacin and Anxiety. The study, published in The New England Journal of Medicine, examined 50- to 80-year-olds with cardiovascular disease. Niacinamide, also called nicotinamide, is a form of vitamin B-3, an essential nutrient. According to NIH, it is also used for treating migraine headaches, circulation problems and dizziness, and to reduce the diarrhea associated with cholera. Press question mark to learn the rest of the keyboard shortcuts, repair damage to the brain caused by strokes, improve the ability to maintain an erection, British Columbia Drug and Poison Information Center, https://www.isom.ca/wp-content/uploads/2013/01/Niacin-for-Detoxification-A-Little-known-Therapeutic-Use-26.2.pdf. But a large-scale 2014 study has caused some health professionals to revisit that view. Niacin can help boost HDL (good cholesterol) and lower triglycerides which is important for cardiovascular health. And large doses of niacin on an … There's good evidence that it helps reduce atherosclerosis, or hardening of the arteries in some people. It depends on the concentration of the ingredient, the overall formula of the product, what skin concern(s) you’re trying to tackle, and of course, your skin! - so just apply the product as you normally would. Namely, vitamins. Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. THC is broken down in the liver into its metabolites which are then transported to the bloodstream, brain, and other organs. If you flush beet red for half an hour and feel weird, well, you took too much. For people who have already had a heart attack, niacin seems to lower the risk of a second one. Press question mark to learn the rest of the keyboard shortcuts, Mod | Hoojoo specialist | Neem Team Queen. According to a study published in the Journal of Sexual Medicine, vitamin B3 was found to improve the ability to maintain an erection in men with moderate to severe erectile dysfunction. It sucked! Journal of Cosmetic and Laser Therapy, 8:2, 96-101. doi:10.1080/14764170600717704, 11 - Fabbrocini, G., Cantelli, M., & Monfrecola, G. (2014). It takes time for products to work. Despite niacin's ability to raise HDL, research suggests that niacin therapy isn't linked to lower rates of death, heart attack or stroke. Don't spam your blog, your product, your anything, Press J to jump to the feed. New comments cannot be posted and votes cannot be cast, More posts from the plantmedicines community, A open space to gain and the share knowledge on Plant Medicines. We're super thankful for their help in the Niacinamide Research Thread!! Facilitating facial retinization through barrier improvement. Vitamin B-3 helps maintain all of the … (2006). Niacin --> not a plant medicine but a vitamin (b3), powerful for detoxification and has a multitude of other benefits, some are helping with cholesterol in the body, with strokes ad certain cancers, but also causes a strange hot, tingling, flushing sensation! It’s not just any other vitamin, it is vitamin B3, which is a very important nutrient as every part of your body needs it to function properly. Influence of niacinamide containing formulations on the molecular and biophysical properties of the stratum corneum. The authors of the study conclude that doctors should take these adverse effects into consideration when prescribing niacin and perhaps niacin should only be used to treat severe patients. "If you take too much you can have side effects including nausea, stomach upset, abnormal liver tests, headaches, muscle breakdown and flushing — usually with over 1 to 2 grams per day." Niacin — also known as vitamin B-3 — helps break down nutrients into energy. COSRX Galactomyces 95 Whitening Power Essence, Superdrug Calm Skin De-Stress Refreshing Facial Spritz, Casual Friday (Humor, Cringe, Selfies, B&As are allowed; General Chat). Ischemic stroke is caused by an obstruction within a blood vessel supplying blood to the brain and accounts for 87 percent of all cases. The normal recommended daily allowance (RDA) of niacin is dependent on age, gender, health conditions and reproductive status. Niacin, in the form of niacinamide, is cheap, it is safe, and it seems to reduce anxiety and is widely available. While NR may have some additional benefits above and beyond those offered by nicotinamide, this type of vitamin B3 also clearly lacks some of the beneficial qualities of its origin substance. In my case, I enjoyed the flush and noticed some positive effects. \"Niacin has a role in producing certain hormones in the adrenal glands and helps remove harmful chemicals from the liver,\" Dr. Sherry Ross, women's health expert at Providence Saint John's Health Center in Santa Monica, Califor… International Journal Of Dermatology, 34(6), 434-437. doi:10.1111/j.1365-4362.1995.tb04449.x, 3 - Zabiolah Shahmoradi, A. It’s one of the many B vitamins. (2011). If you take too much niacin, the flush may be more pronounced and longer lasting. (6) In addition, it plays a role in gland and liver function. Journal Of Cosmetic Dermatology, 6(4), 243-249. doi:10.1111/j.1473-2165.2007.00342.x, 5 - Hakozaki, T., Minwalla, L., Zhuang, J., Chhoa, M., Matsubara, A., & Miyamoto, K. et al. Dry/Sensitive | Mod | European | Patch test ALL the things! However, this may cause flushing/skin redness - if that occurs, you can use niacinamide in a separate part of your routine (i.e. (4) So what is a niacin flush? High cholesterol. Topical nicotinamide for seborrheic dermatitis: an open randomized study. Having enough niacin, or vitamin B3, in the body is important for general good health. Comparison of topical 5% nicotinamid gel versus 2% clindamycin gel in the treatment of the mild-moderate acne vulgaris: A double-blinded randomized clinical trial. They were already taking statin medication, which was combined with extended-release niacin and laropiprant, which reduces face flushing associated with niacin, for four years. Below you will find a more detailed and objective description of the effects and benefits: " Vitamin B3, also called niacin, is one of the eight B-complex water-soluble vitamins. See our Holy Grail niacinamide recommendations: COSRX Galactomyces 95 Whitening Power Essence (2%), Garden of Wisdom Niacinamide & B5 Serum (3%), Silk Naturals Super Serum (just under 4%), Face Theory Cera-C Pore Reducing Toner (5%). Niacin side effects can include a niacin flush, which is when someone temporarily experiences red, warm and tingling burning and/or itchy skin after taking a niacin supplement. The flushing is harmless and usually subsides within one or two hours, according to the British Columbia Drug and Poison Information Center (DPIC). This is when you should generally expect to see a positive difference in your skin - which isn't the same as your skin being exactly as you want it to be! Niacin, a name coined from nicotinic acid vitamin, comes in several forms, including niacinamide (nicotinamide) and inositol hexanicotinate. Apparently niacin is a good treatment for mental disorders such as schizophrenia, depression, and anxiety according to several sources online. Journal Of Research In Medical Sciences : The Official Journal Of Isfahan University Of Medical Sciences, 18(2), 115. A B-3 deficiency can lead to disorders of the skin, kidneys, and brain. One side effect of taking niacin supplements is mild flushing. Niacinamide, which is also called nicotinamide, is one of two major forms of vitamin B3 (niacin) found in supplements (the other is nicotinic acid). Those taking medications or those that have medical conditions should contact a medical professional before taking niacin due to drug interactions and side effects. A 2017 article in the Journal of Clinical-Lipidology, however, cited previous studies that saw reductions in cardiovascular events in patients that combined niacin with statins. Niacin has other benefits. Niacin is a member of the vitamin B group, known as B3 (since it was the third in the group to be discovered). However, this type of niacin may cause liver damage in some people, according to the DPIC. The cream was also found to help treat acne. "When taking it, you need to check for interactions with other meds and make sure your labs tests are normal," said Dr. Kristine Arthur, internist at Orange Coast Memorial Medical Center in Fountain Valley, California. It may affect blood vessels in the retina and subsequently help prevent age-related macular degeneration. There is a lot of secrecy around vitamin therapy, and the history of … Food sources of niacin include yeast, meat, fish, milk, eggs, nuts, green vegetables, beans and enriched breads and cereals. The authors attribute this protection to niacin's anti-inflammatory and anti-angiogenic effects. (2006). (2002). Some use it regularly because they are “overmethylators” and some use it intermittently when they experience symptoms they associate with overmethylation. Therefore, niacin has been a major part of treating high cholesterol for at least 50 years. According to Hoffer, 90% of acute schizophrenics (i.e., those who have been sick less than 2 years or have had several remissions a… In a double-blind trial by the State University of New York, the topical application of a 4 percent niacinamide gel twice a day for two months resulted in a similar acne improvement when compared to 1 percent clindamycin gel. Niacin is known for lowering LDL (bad) cholesterol and triglycerides in the blood. Journal of Dermatological Treatment, 25:3, 241-245. doi:10.3109/09546634.2013.814754. Note: Low pH products (like ascorbic acid based Vitamin C serums) are fine to use with niacinamide. A recent study found that nicotinamide significantly reduces the incidence of nonmelanoma skin cancers in those with a history of basal cell carcinoma or squamous cell carcinoma. Niacin benefits also include the vitamin’s ability to decrease inflammation and boost blood circulation. As a loose guideline, below are some time frames for common skin concerns that can be addressed with niacinamide. Additionally, the Mayo Clinic reported that niacin could raise HDL (good) cholesterol by more than 30 percent. Vitamin B3 is known for increased alertness, clarity, focus, memory, enhanced mood and energy, is a potent antioxidant and free radical scavenger, lowers LDL-cholesterol, increases HDL-cholesterol and lowers triglycerides Vitamin B3 (Niacin, nicotinic acid, 3-pyridine-carboxylic acid) is one of eight B-Vitamins. A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma. It also was associated with a higher risk of death from all causes and serious side effects, including liver problems, excess bleeding, infections, loss of blood sugar control in diabetics, gout and the development of diabetes. It has minimal irritation potential, is generally easy to introduce into a routine, and can help tackle a wide range of issues. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Research suggests that large doses of niacin may have other health benefits. Niacin deficiency (pellagra). Niacin is vitamin B-3, one of the water soluble B-complex vitamins. It does this by stopping the … Niacin Flush Benefits for Cholesterol & Triglycerides. 1 - Khodaeiani, E., Fouladi, R., Amirnia, M., Saeidi, M., & Karimi, E. (2013). Getting too much niacin is possible, even for healthy individuals. AM instead of PM), or you can simply wait a bit longer before applying niacinamide! Specifically Niacin. Niacin is a good thing to take long-term, as it lowers cholesterol, results in higher NAD levels, etc. Cutis, 78 4, 275-81, 8 - Tanno, O., Ota, Y., Kitamura, N., Katsube, T., & Inoue, S. (2000). Lowers Triglycerides. I've also seen many positive reports of its efficacy online usually with the only side effect being the uncomfortable, burning niacin flush. Anecdotally, it is claimed by some that niacin reduces anxiety and depression, while promoting calmness and better sleep. A 2000 study published in the journal Stroke also used rats and found that treatment with nicotinamide may repair damage to the brain caused by strokes. Niacinamide is one form of vitamin B3 (niacin) that plays an important role in energy metabolism and cell health. Maybe only 50mg just to check. "Niacin has a role in producing certain hormones in the adrenal glands and helps remove harmful chemicals from the liver," Dr. Sherry Ross, women's health expert at Providence Saint John's Health Center in Santa Monica, California, told Live Science. Niacin (vitamin B3) is a colorless hydrophilic organic compound classified as an essential dietary nutrient among humans. One of niacin’s unique properties is its ability to help you naturally relax and get to sleep more rapidly at night. A big emphasis on only 100mg max the first time. When you can expect niacinamide to start working can be tricky to figure out! Niacin has a wide range of uses in the body, helping functions in the digestive system, skin and nervous system. Niacin (Niaspan, Niacor) is an oral drug mainly used to lower cholesterol levels. There is total lack of scientific evidence that Niacin has any immediate benefits, when it comes to eliminating THC. For women and men, the average RDA is 14 to 16 milligrams a day, according to the NIH. Each of these forms has various uses as well. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. The 2017 study, published in Scientific Reports, found that rats that were given niacin and then induced with colitis saw less colonic damage than those who did not receive niacin. If you don’t start to see at least some improvement after the given time frame, you may want to try a stronger product, or a different ingredient! In a world filled with depressed and anxious people, there might be a role to play for this little hero of a vitamin. By using our Services or clicking I agree, you agree to our use of cookies. Had to share, it benefits me I feel. In addition, niacin is an FDA-approved treatment for pellagra, a rare condition that develops from niacin de… 2. Prescription niacin is used to increase high-density lipoprotein (HDL) cholesterol — the \"good\" cholesterol that helps remove low-density lipoprotein (LDL), the \"bad\" cholesterol, from your bloodstream. Detoxification is the process by which toxins are removed from the body by being broken down and excreted through urine, saliva, sweat, perspiration, and stool. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. Some over-the-counter niacin tablets deliver the dose in a short burst, which makes the reaction more intense. Niacin has many health benefits which is why many dietary supplements contain niacin. British Journal Of Dermatology, 143(3), 524-531. doi:10.1111/j.1365-2133.2000.03705.x, 9 - Mohammed, D., Crowther, J.M., Matts, P., Hadgraft, J., & Lane, M. (2013). Timed-release tablets deliver the vitamin more slowly, which reduces the intensity of the flushing. If you’re looking to lower your blood lipids (cholesterol and triglycerides) in a cost-effective manner, niacin flush benefits even extend to this, as taking 1,000 to 3,000 mg a day could lower your “bad” low … The effect of 2% niacinamide on facial sebum production. Want to treat acne, fine lines, dark spots, or redness? 87% of those users who reviewed Niacin reported a positive effect, while 11% reported a negative effect. Unfortunately far too many people don’t understand the emotional and potential mental benefits that go along with niacin. Niacin also can play a part in improving health. In fact, it’s believed that vitamin B3 in the form of niacinamide benefits diabetes by improving the function of beta cells, which are the cells that are responsible for the production of insulin. It has minimal irritation potential, is generally easy to introduce into a routine, and can help tackle a wide range of issues. The symptoms of pellagra include digestive problems, inflamed or flakey skin, diarrhea and mental impairment. In the United States and other developed countries, niacin deficiency is rare and is typically found in alcoholics.